Phosphoric acid functionalized mesoporous organo-silica (EPO) as the adsorbent for in situ enrichment and isotope labeling of endogenous phosphopeptides.

نویسندگان

  • Hongqiang Qin
  • Fangjun Wang
  • Peiyuan Wang
  • Liang Zhao
  • Jun Zhu
  • Qihua Yang
  • Ren'an Wu
  • Mingliang Ye
  • Hanfa Zou
چکیده

Ti(4+)-EPO nanoparticles were adopted as the adsorbent for in situ solid phase enrichment and isotope labeling of endogenous phosphopeptides, which has great potential application in high-throughput analyses of biological samples for screening and discovery of disease-specific biomarkers.

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عنوان ژورنال:
  • Chemical communications

دوره 48 7  شماره 

صفحات  -

تاریخ انتشار 2012